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『洗冤录』着于宋代，是法医史上的惊世巨着，而其作者竟是一个饱受歧视的棺材遗腹子，三十岁前，他一直靠打更为生，不料一宗命案却改变了他的命运……

宋慈（欧阳震华）与劫富济贫的江湖女贼唐思（宣萱），意外地卷入了谋杀村长案中，被判死刑，後得到新知县宋翊（林文龙）及熟悉验尸的马贵相助，沉冤得雪。翊聘慈为忤工，两人合作下屡破奇案，声名大噪。另思因翊再造之恩，暗生情愫，但翊已与聂枫（陈妙瑛）发展感情。

其後一名长相与翊一模一样的人突然出现，原来翊为求功名，冒充知县，为掩饰罪状，翊将真宋翊杀死，又攀附权贵，抛弃枫而娶富家女蓝彩蝶为妻，岂料蝶家早已外强中乾，负债累累，翊有感蝶为其负担，故设计陷害。翊的奸险面目渐渐表露，但每次行凶时均非常谨慎，彻底毁尸灭迹，慈无计可施之际，竟意外地发现了真宋翊的尸体，究竟慈能否将翊绳之以法呢？

KO LAP-YAN (Alex Fong) pulls himself together following his wife’s death, and changes his job, becoming a Consultant of Forensic Psychiatry Department. As soon as he assumes his office, he cooperates with another Consultant, Dr. CHEUK WAI-KIU (YoYo Mung), conducting clinical evaluations and treatments on a mentally ill patient. During the examination, a felony involving an evil cult is unveiled, so LAP-YAN joins forces with LAM CHUNG-YAN (Tavia Yeung), an Inspector of Regional Crime Unit, to probe into the matter. Gradually, a subtle bond between Department of Forensic Psychiatry and the Regional Crime Unit becomes established. Each time she encounters a convoluted case, CHUNG-YAN goes to seek aid from LAP-YAN, whereas WAI-KIU seeks advice from LAP-YAN whenever she has relationship problems. Furthermore, with the spiritual support from his good colleagues as well as good friends, LIN CHI-SUM (Ram Chiang) and LEUNG KAI-WING (Edwin Siu), LAP-YAN actively turns over a new leaf. Out of the blue, while a horrific serial murder case stirs up some turbulence, LAP-YAN discovers that there is an utmost connection between the case and CHUNG-YAN. 高立仁 (方中信) 丧妻后重拾斗志，转职成为法医精神科的顾问医生，甫入职便与另一顾问医生卓慧翘 (蒙嘉慧) 合作，为一名精神病患者提供临床评估及治疗，过程中揭发一宗涉及邪教的严重罪行，因而与重案组探员林颂恩 (杨怡) 联手调查，法医精神科渐与重案组建立微妙的合作关系，颂恩每遇棘手案件会找立仁帮忙，而慧翘每遇感情烦恼亦会找立仁解困，加上两位好同事兼好友连志森 (蒋志光) 和梁启荣 (萧正楠) 的精神支柱，令立仁积极重建新生活，谁料一宗恐怖连环凶杀案牵起波澜，立仁竟发现案件与颂恩有莫大关联……

Main cast: 马国明,胡杏儿,吴卓羲,徐子珊,胡定欣 Director: 关永忠 Total Episodes: 20 Audio Tracks: Cantonese, Mandarin Subtitle: English, Chinese Rated: PG Studio: TVB Release Date: 27/3/13 Production Year: 2013 Running Time: Approx. 1200 min (20 Episodes) No. of Disc: 4