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反黑組高級督察張國鋒 (郭晉安) 疾惡如仇，心思細密，分析力強，天生是當警察的好材料。他熱愛工作，甚至因工作的緣故而犧牲了家庭。重案組督察周家榮 (張家輝) 是鋒的同僚兼好友，以殲滅天下壞為已任。鋒與榮在工作上雖時有争执，但卻無阻二人的合作無間，錢雅麗 (袁潔瑩)，本以為加入了鋒的反黑組后可以一展所長，怎料鋒初始只委派她文書工作，令她滿不是味兒，對于鋒和榮，麗初期全無好感，因她以為鋒是拋妻棄子的負心漢，榮則是私生活不檢點的人，工作上合作多了，三人對大家的認識也隨之而增加，榮熱烈追求麗，麗與榮相處下去卻受不了榮凡事要求十全十美的性格。此際麗發現自己愛上了鋒，卻因為榮母去世而不忍離開榮。一段復雜的三角關系出現了，簡單的麗不懂處理，向鋒道明，鋒卻不想橫刀奪愛。此事更讓榮知道了，弄至兄弟鬩場…...

Gossip magazine journalist Tong Leung-sing (Sammy) has unfortunately lost his left ear in a traffic accident. He gains mystical rat power after undergoing transplant surgery. Leung-sing keeps creating fake news just to benefit himself. He clashes with righteous policewoman Sung Hoi-yan (Priscilla Wong), causing both of them to lose their jobs. With the support of her uncle Ming Kwan-ngai (KK Cheung), Hoi-yan becomes a private investigator. Leung-sing is forced to help Hoi-yan with her investigation activities as Hoi-yan catches him using his mystical power to peep at goddess Ming Cheuk-kei (Zoie Tam). Gold digger Tong Mei-fun (Kamen Kong) is cruelly harassed as rich clan heir Tsui Tsun-wai (Daniel Chau) and she become foes. Mei-fun forgives Tsun-wai and offers to help him as Tsun-wai gets into a difficult situation. Leung-sing becomes increasingly arrogant as he uses to his mystical power to solve cases. Meanwhile, Hoi-yan shockingly finds out Kwan-ngai’s real character. Leung-sing faces the danger of exhausting his mystical power and becoming a rat as he helps Hoi-yan. 八卦雜誌記者唐亮星（森美飾）因交通意外痛失左耳，接受移植手術後獲得老鼠超能力。亮星為功利造假新聞，與滿腔正義的女警宋凱甄（黃翠如飾）發生衝突而雙雙失業。凱甄得舅父明君毅（張國強飾）鼓勵，轉當私家偵探。亮星用超能力偷窺女神明卓淇（譚凱琪飾），被凱甄抓住，被迫助她查案。拜金女唐美芬（江嘉敏飾）與富家子隋俊偉（周志康飾）結怨，慘被百般戲弄。俊偉落難，美芬不計前嫌施援手……亮星利用超能力破案，漸漸自大起來！此時凱甄驚悉君毅真實一面，亮星相助卻陷入超能力耗盡，變成老鼠的危機！