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Rewind seven years and two families are ruined due to a serious traffic accident, causing destinies of Keung Yuk-shing (Frankie Lam) and Fong Lok-man (Priscilla Wong) to be rewritten. Fast-forward seven years and because of a traffic accident, Yuk-shing runs into Lok-man again. Life is still filled with ups and downs. Lok-man and her younger sister Fong Shu-man (Shiga Lin) do not get along like they used to as people close to them are leaving one after another. An eccentric doctor by the name of Koo Hei-san (Mark Ma) unexpectedly manages to get to the bottom of the problem. Lok-man is busily looking after her daughter Chu Hang-yee and stepson Chu Ka-bing (Zeno Koo). Yuk-shing, on the other hand, never understands the needs of his only daughter Keung Tsz-yau (Chloe So). Fate brings Tsz-yau and Ka-bing together. Their mutual friend Mok Yu-him (Kyle Li) comes across even more problems because of their relationship, which also causes the truth about a traffic accident that took place all those years ago to gradually surface. The chums even have to prepare for change again.

七年前一宗嚴重車禍，破壞了兩個家庭，改變了姜煜誠(林文龍飾)、方樂汶(黃翠如飾)的人生。七年後一次交通意外，讓煜誠重遇樂汶，生活仍然有悲有喜。樂汶與妹妹方書文(連詩雅飾)因身邊人逐一離開而鬧僵，沒想到行為怪異的醫生古希晨(馬貫東飾)，卻能直搗問題根源。樂汶忙於照顧女兒朱幸而及繼子朱嘉炳(顧定軒飾)，煜誠則一直未能了解獨女姜子優(蘇皓兒飾)的需要。子優和嘉炳因緣走近，共同朋友莫宇謙(李任燊飾)竟為此段關係衍生更多問題，也令當年車禍真相漸漸浮現，眾人亦要再次面臨改變……