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Senior Chemist of Forensic Science Division Ko On (Raymond Wong), Senior Forensic Pathologist Man Ka-hei (Selena Lee) and Kowloon West Regional Crime Unit Senior Inspector Kwok Fai-wong (Shaun Tam) are the pillars of Crime Busting Trio leading a team of outstanding individuals. They unravel appalling schemes by using advanced forensic science. Their mastery of pathology enables them to decode secrets of the human anatomy. Their strict adherence to upholding the law never fails to uncover shocking truth about criminal acts! Unhappy childhood experience of enthusiastic reporter Tsui Yi (Roxanne Tong) surprisingly had something to do with Ko On. Seasoned forensic pathologist Queen (Alice Chan) becomes a murder suspect as she is betrayed by her lover. Mysteries and bewildering cases become intertwined. Scenes of cold-blooded acts are simply horrific. The baddies think they may get off the hook. The Crime Busting Trio motto is “Good always triumphs over evil and embrace compassion amid animosity”. They are determined to make statements on behalf of the deceased and seek justice for survivors! 香港法證部高級化驗師高安(黃浩然飾)、法醫科高級醫生聞家希(李施嬅飾)、西九龍重案組高級督察郭輝煌(譚俊彥飾)，這「滅罪鐵三角」帶領著精英團隊，用專業的法證科學，揭示驚人的預謀策劃；用精密的法醫知識，破解隱蔽的人體密碼；用嚴謹的執法精神，披露震撼的罪惡真相！ 熱血記者徐意(湯洛雯飾)，童年憾事竟與高安緊扣牽連；法證專才水慧明(陳煒飾)，遭至愛背叛頓成殺人疑兇… 謎團奇案，重重交錯；冷血兇徒，幕幕驚心！人在做，天在看！「滅罪鐵三角」堅守「邪不勝正，惡不抵善」的信念，誓為死者發聲，替生者雪冤！